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The action of glutathione on oxidative stress has led to speculation on the possible therapeutic role of this molecule for several chronic diseases with altered redox balance

Human iPS cell-derived cartilaginous tissue spatially and functionally replaces nucleus pulposus

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GPx-1 acts in the intracellular environment and maintains the physiological level of hydrogen peroxide, which is important in mitochondrial function, thiol redox homeostasis, and signal transduction (Brigelius-Floh and Maiorino 2013)