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Ozempic is injected into the skin of the belly, thigh, or upper arm once a week

Unlike earlier GH secretagogues, ipamorelin exhibits high selectivity, minimal activity at other hormonal axes (ACTH, cortisol, or prolactin), and potent GH release in both animals and humans

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For people with type 2 diabetes, the SURPASS trial series demonstrated exceptional glycemic control alongside weight loss, which is why the compound received its first approval for diabetes before the obesity indication followed

"Small molecule nicotinamide N-methyltransferase inhibitor activates senescent muscle stem cells and improves regenerative capacity of aged skeletal muscle." Biochemical Pharmacology