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Further, -LA can provide additional antioxidant effects by recycling both vitamin C and vitamin E (Coombes et al., 2000)

Heredity seems to play a part, and the onset of symptoms seems to coincide with times of significant hormonal upheaval, such as during puberty, pregnancy and menopause (Szel et al, 2014)

Another enzyme, Catechol-O-methyltransferase (COMT), transfers a methyl group to catechol compounds, thereby producing S-adenosyl homocysteine (SAH), a homocysteine precursor