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doi: 10.1186/s12951-021-00897-2 112 ZhangF.ZhuangJ.LiZ.GongH.De vilaB

Additionally, research indicates that Safflower yellow, a major active constituent of Carthamus tinctorius L., can influence HCC progression by modulating the GM and enhancing hepatic immune infiltration [16]

Experience gained from RAF and MEK inhibitors that have been applied in the clinic and extensively studied in their resistance mechanisms could provide important insights into the resistance mechanisms to KRAS (G12C) inhibitors 229