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of the preamble of the FY 2023 IPPS/LTCH PPS final rule with comment period for a detailed discussion on the adoption of the 10-percent cap policy (87 FR 49152 through 49154)

The combination of BSO+L-PAM achieved synergistic cytotoxicity (combination index number (CIN) 0.7) and induced 24 logs of cell kill in all nine MM cell lines including the eight lines established at progressive disease (PD) after therapy (U266, OPM-2, NCI H929, KMS-12-PE, EJM, TX-MM-030h, MM.1S and MOLP-2), 25 which include lines with cytogenetic profiles associated with a poor prognosis (Figure 1b)

To assess the impact of GSH treatment on OXA-induced ALI, mice (n=10 per group) were treated with OXA (10 mg/kg, i.p.) and GSH (400 mg/kg, i.p., 30 min prior to first OXA injection) for 4 days (once daily until the end of the experiment)

Activation of this axis has been shown to contribute markedly to endothelial dysfunction, hepatocyte necrosis and impaired liver regeneration in HIRI