l-carnitine function fatty acid transport mitochondria The Role of in and β -oxidation in Role of Carnitine Shuttle System

The methyl group changes the original molecule into something different

*Correspondence: Jun Liao, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

When possible, peripheral GSH measurements were converted to M, Mol/gHb, or Mol/g protein as appropriate

Moreover, the NRF2 mRNA level showed a positive correlation with the mRNA level of antioxidant enzymes in these studies (Reference Jiang, Chen and Liu33Reference Chen, Feng and Jiang35)

Oxidative stress-mediated liver injury includes depletion of hepatic GSH levels, together with the disruption of other antioxidant defence mechanisms, leading to overproduction of ROS, thus provoking hepatocellular damage observed in DILI