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The following predictors informed an unsupervised machine learning algorithm (k-means clustering): age, BMI percentile, waist circumference (WC), systolic blood pressure (SBP), uric acid, alanine aminotransferase (ALT), aspartate aminotransferase (AST), fasting triglycerides, very low-density lipoprotein (VLDL), LDL, and homeostatic model of insulin resistance (HOMA-IR)

The GLP-1 agonists are also being investigated for efficacy in neurodegenerative diseases including Alzheimers and Parkinsons diseases [28]

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