foxo4-dri human study Frontiers FOXO4-DRI PEPTIDE 2MG/5MG/10MG VIAL –

G.JessbergerS

Epithalons potential role: Research suggests this peptide may help bridge the gap between chronological and biological age by supporting the cellular mechanisms that maintain telomere length

Common (Generally Mild) Nausea Vomiting Headache Mild sedation GI discomfort related to PN Metabolic Effects Elevated homocysteine (risk factor for thrombosis) Metabolic acidosis Hyperammonemia (especially in hepatic dysfunction) Elevated BUN/creatinine Hyperglycemia (from PN carbohydrates) Rare / Serious Hepatic dysfunction Allergic reactions to PN components Central line complications (infection, thrombosis) Refeeding syndrome (hypophosphatemia, hypokalemia, hypomagnesemia) Neurologic symptoms if severe ammonia elevation occurs Pregnancy & Breastfeeding Pregnancy Methionine is naturally required in pregnancy, and PN is considered safe and appropriate when medically indicated

Feron, O., Dessy, C., Moniotte, S., Desager, J

Only data from the second wave are described in this current study