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In most diseases, ROS appear to have a direct connection with inflammaging and cell senescence, and oxidative stress and inflammaging increase the aging-related phenotype, and induce and aggravate the inflammatory response, creating a chronic state of systemic inflammation (290297)

Mar 2004;251(3):261-268

Pelvic floor physical and occupational therapy plays a crucial role in identifying the mechanical impairments that are affecting the nerve

Interestingly, the perception of swelling or edema without visible findings in fibromyalgia could also contribute to her sensory complaints