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Cazenave-Gassiot et al., Mfsd2a is a transporter for the essential omega-3 fatty acid docosahexaenoic acid

At the molecular level, CAY10603 inhibits the activation of NLRP3 and caspase-1 induced in HK-2 cells and iBMDM, effectively alleviating NLRP3-mediated macrophage pyroptosis