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Additionally, the experimental and TDDFT simulations of the pre-edge (Fig

This result is surprising because H 2 O 2 treatment creates an oxidative environment, whereas a decrease in TPI activity shifts the NADPH/NADP+ ratio towards a reductive environment (Ralser et al

They found that high activity only with GSTA1, moderate activity with GSTM3 and GSTM1 and no significant conjugation by any of the other isoforms studied