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Notably, the corresponding mechanistic relationships remain to be elucidated

10.3390/medicina58020299 119 VisserenF

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25Hydroxycholesterol is reported to play a regulatory part in the biosynthesis of sphingomyelin, which is required with cholesterol for the formation of raft sub-domains in membranes, where signalling molecules are concentrated, and together with other oxysterols, such as 24 S ,25-epoxycholesterol, to regulate the hedgehog proteins in embryonic development