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Recent analyses highlight that tofersen not only validates the genetic approach but also enhances therapeutic opportunities by potentially altering the disease course when initiated early, though accessibility and long-term management strategies remain areas for development (46)

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Non-surgical options for Peyronies disease For men who have issues with curvature causing embarrassment or inability to penetrate, pain, erectile dysfunction, and/or penile shortening, the following non-surgical treatment options are available: Oral medications Pentoxifylline is a commonly used oral therapy that inhibits some inflammatory proteins responsible for abnormal scar formation