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Preclinical studies combining BPC-157 with growth hormone demonstrated enhanced healing compared to either agent alone, consistent with BPC-157's mechanism of upregulating growth hormone receptor expression

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In the hippocampus, BPC 157 strongly elevates Egr1 , Akt1 , Kras , Src , Foxo , Srf , Vegfr2 , Nos3, and Nos1 expression and decreases Nos2 and Nfkb expression