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Description

Inducing ubiquitination and degradation of TrxR1 protein by LW-216 promotes apoptosis in non-small cell lung cancer via triggering ROS production

While the clinical trials demonstrated excellent safety in generally healthy obese adults, individual medical histories may reveal concerns not apparent in trial populations

This method comprises administering to the subject an effective amount of a compound selected from the group consisting of Suitable and preferred subjects are as disclosed herein

doi: 10.1126/SCISIGNAL.3001127 72 MarquesOPortoGRmaAFariaFCruz PaulaAGomez-LazaroMet al

Administration of resveratrol suppresses malondialdehyde (MDA) and nitric oxide (NO) levels and restores glutathione (GSH) levels and superoxide dismutase (SOD) activity (Zhang et al., 2019)