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This study evaluates the hypoperfusion intensity ratio (HIR) on perfusion MRI as a biomarker for ICAD and integrates it into a machine learning model to enhance predictive accuracy

Q: Is it safe

however, there were important limitations to consider, including small sample sizes, a lack of long-term observation, the use of a single species or strain, the lack of in-depth exploration of cellular or molecular mechanisms, failure to assess other aspects of reproductive function, a lack of validation of the clinical relevance, and a failure to consider individual differences in drug dosages