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In the FPN-treated group, we observed darker, larger cells with thickened interdigitated processes and a significant increase in the mean area percentages of GFAP-positive immunostained cells in cerebral and cerebellar tissues relative to the control rats

[3] [6] In the context of aging skin, oxidative damage and low-grade inflammation are plausible contributors to matrix degradation, so an agent that modulates both is mechanistically attractive

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Yasui-Furukori, N., Hidestrand, M., Spina, E., Facciol, G., Scordo, M