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This is the same ECM (extracellular matrix) scaffolding that gives young skin its firmness and bounce

Identification of candidate angiogenic inhibitors processed by matrix metalloproteinase 2 (MMP-2) in cell-based proteomic screens: disruption of vascular endothelial growth factor (VEGF)/heparin affin regulatory peptide (pleiotrophin) and VEGF/connective tissue growth factor angiogenic inhibitory complexes by MMP-2 proteolysis

Substance Withdrawal : Some promising, albeit small, studies in humans have suggested DSIP may help alleviate withdrawal symptoms from alcohol and opiates.

Pairs well with hydration, soothing, and barrier-support actives

For Tirzepatide users, its gut-protective effects make it particularly relevant