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Proc Natl Acad Sci USA 83:45764579 Jiang Y, Luo Z, Gong Y, Fu Y, Luo Y (2023) NAD(+) supplementation limits triple-negative breast cancer metastasis via SIRT1-P66Shc signaling

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Ras, a signal transduction activation switch, is reportedly mutated in 30% of HCC cases, suggesting that genetic alterations strongly contribute to HCC