glutathione protein modification S-Glutathionylation Glutathione-Triggered Unleashing of Protease K

Mitochondrial superoxide radicals mediate programmed cell death in Trypanosoma cruzi : cytoprotective action of mitochondrial iron superoxide dismutase overexpression

Proc Natl Acad Sci USA 116(7):26722680 Feng H, Stockwell BR (2018) Unsolved mysteries: how does lipid peroxidation cause ferroptosis

We observed that IGF-1 treatment of Th17 cells from IGF-1R cKO mice did not decrease TMRE, as it did in Th17 cells from control mice (Fig

Indeed, overexpression of Notch pathway members in the mouse liver, alone or in combination, drives CCA development 136,137,138,139

Chronic hypoxia drives the conversion of Tregs to pro-inflammatory Th17 cells via the HIF-1 pathway, characterized by reduced CD25 expression, increased OX40 expression, and exhaustion of immunosuppressive function, which exacerbates Th1/Th17 cell polarization and the release of pro-inflammatory factors such as IL-17A and IFN- (Lantz et al., 2024)