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Mechanistically, FA reacts with the redox-active thiol group of glutathione (GSH), altering the GSH:GSSG ratio and causing oxidative stress

Biological activities of fibroblast growth factors

PMID: 3029331

4 A decade of progress: novel antifungal drugs targeting resistance The main mechanism of antifungal action lies in inhibiting essential molecules, such as ergosterol (azole class) or 1,3--D-glucan (echinocandins), or by binding to ergosterol (polyene class), leading to the formation of pores and altering the integrity and permeability of the cell membrane, thereby affecting the membrane or fungal cell wall

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