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In contrast, Rab4 inhibited with 3-pyridinyl ethylidene hydroxyl phosphonocarboxylate (3-PEHPC) restores Drp1 function via the mTOR-independent pathway, reversing mitochondrial accumulation in lupus T cells ( Increased calcium flux also promotes oxidative stress-dependent T cell activation

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Bulfamante G, Chiumello D, Canevini MP, Priori A, Mazzanti M, Centanni S, Felisati G (2020) First ultrastructural autoptic findings of SARS -Cov-2 in olfactory pathways and brainstem

NRF2 target genes share a common DNA sequence known as the antioxidant response element (ARE) in their promoter regions that is required for NRF2 binding and gene induction [37]

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