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Moreover, the administration of DSS caused the further increase of Biosynthesis of vancomycin group antibiotics and Streptomycin biosynthesis pathways in the EpCAM +/ mice, although the pathway of Biosynthesis of ansamycins was reduced in EpCAM +/ mice with the treatment of DSS (Figure 6A)

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The same vascular growth activity raises a biologically plausible concern: accelerating angiogenesis in a tissue that already harbors occult or established malignancy could support tumor growth