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doi:10.1111/hpb.12277 Ismail, Ola Z, and Vipin Bhayana

doi: 10.1155/2013/797914

Tumor cells with high GGT expression demonstrate notable oxidative stress tolerance without DNA damage, while clones with low GGT expression exhibit increased sensitivity to oxidative stress and apoptosis (93)

It primarily manifests as motor symptoms due to the degeneration of dopamine-producing neurons in the substantia nigra pars compacta (SNpc), including tremors, bradykinesia (slowness of movement), muscle rigidity, and impaired coordination