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doi: 10.1016/j.celrep.2021.109721 69

Glasson N, De Sandre C, Pantet O, Reinhard A, Lambercy K, Sandu K, et al

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30 percent or more is considered TEN

Recent studies have demonstrated that tenuigenin suppresses caspase-3 activation by downregulating the expression of JNK and phosphorylated JNK in neuronal cells (Chen et al., 2010), thus reversing the expression ratio of Bcl-2 to Bax (Ren et al., 2022)