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SKU: 50850675585
Price: 27.09 USD
Availability: InStock
Rating: 4.2196 (19 reviews)

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Description

Homology-independent targeted insertion (HITI) enables guided CAR knock-in and efficient clinical scale CAR-T cell manufacturing

Treatment with roflumilast for 4 days significantly attenuated unfavorable changes in these parameters

Moreover, it has been previously shown that GPX4 overexpression in cancer cells inhibits RSL3-mediated ferroptosis, whereas GPX4 deletion increases susceptibility to ferroptosis [22]

On the one hand, mutant p53 can suppress the expression of apoptosis-related genes (such as Puma), helping tumor cells evade the apoptosis induced by chemotherapeutic drugs