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Left ventricular cardiac function was assessed by conventional echocardiography to measure left ventricular ejection fraction (LVEF) and two-dimensional speckle tracking echocardiography (2D-STE) to determine left ventricular global longitudinal strain (2D-LV GLS)

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Collagen fibers align with the direction of mechanical loading, and collagen cross-linking increases tendon stiffness and tensile strength

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