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1992 Sep;35(9):813-7

Ying H, Kimmelman AC, Lyssiotis CA, Hua S, Chu GC, Fletcher-Sananikone E, et al

4 Conaway E, Browning B

Vitamin B12 is needed for physical growth and development and for the formation of red blood cells in the bone marrow

While some retrospective studies suggest that metformin may confer a survival benefit for diabetic patients with solid tumors, including PDAC, randomized controlled trials have not found significant benefits for PDAC patients when metformin is combined with gemcitabine [109, 113]