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Animal handling was followed according to Helsenki declaration of animal ethics

It is also known that species such as Bifidobacterium are able to reduce the adhesion of Porphyiromonas gingivalis and that Bifidobacterium lactis would be an antagonist of periodontal pathogens and could be used as an adjuvant in periodontal treatment (Oliveira et al

Within these reactive species we find superoxide anion (O 2 ), hydroxyl radical ( OH), nitric oxide (NO ), as well as other species of non-free radicals such as hydrogen peroxide (H 2 O 2 ), hypochlorous acid (HClO) and peroxynitrite (ONOO )