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Acknowledgments Olawale Ajuwon is supported by the postdoctoral research fellowships from the Claude Leon Foundation and the South African National Research Foundation

Although both exercise and herbal medicine show significant efficacy in treating ALD individually, their potential synergistic effects when combined remain to be further explored

doi: 10.1016/j.intimp.2008.10.021

In summary, GPR146 deficiency confers protection against diet-induced obesity, as demonstrated by reduced fat mass, smaller adipocyte size, and lower circulating free fatty acid levels

Dried metabolite pellets were resuspended in a 45 L 50:50 methanol/water mixture for LC-MS/MS analysis