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Digestive enzymes slowly hydrolyze BNP in the gastrointestinal tract, resulting in continuous butyric acid release [116]

Free radicals are unstable molecules generated by normal metabolism, UV radiation, air pollution, alcohol processing, and physical stress

however, DSMB review of prespecified hepatic events did not identify any confirmed cases of DILI or any liver adverse events related to study drug, and there were no events of liver decompensation

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