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Increased IL-17 expression in degenerated human discs and increased production in cultured annulus cells exposed to IL-1 and TNF-

Meghann Myers is the Pentagon bureau chief at Military Times

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Using microarrays analysis in APC min mice, the same study showed that genes regulating mucosal defence ( Muc2, Klf4 and Tff3 ) were downregulated while pro-inflammatory pathways, especially involving IL23/IL17 signalling, were upregulated (119)