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Clinical application guidelines for female fertility include individualized selection of plant antioxidants based on specific fertility issues (216)

Activated PI3K phosphorylates PIP2 to PIP3, which triggers the phosphorylation of P3-dependent kinase-1/2 (PDK-1/2) at Thr308 and Ser473 residues, resulting in Akt to be recruited to the plasma membrane (Fig