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Studies (54,62,63) of the ChaC family have yielded conflicting findings regarding ChaC expression and its role in tumor tissues, emphasizing the complexity of GSH regulation and function

Fujimoto S, Kurihara N, Hirata K, Takeda T

Conversely, histone deacetylases (HDACs) are capable of removing acetyls from NRF2, thereby reducing its acetylation level and attenuating its transcriptional activity and stability

ROS/mtROS promotes TNTs formation via the PI3K/AKT/mTOR pathway to protect against mitochondrial damages in glial cells induced by engineered nanomaterials