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Brensocatib (also called INS1007 or AZD7986), a DPP1 inhibitor, was found to reduce NE activity in healthy humans (Palmr et al., 2018) and is now in clinical trials for bronchiectasis (NCT03218917) and COVID-19 (EU clinical trial number EudraCT 2020-001643-13)

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& Rotheray, E

T cells Following the identification of macrophages as the culprit of most inflammatory events, studies have found that when the obese phenotype is activated, T cells are involved in the inflammatory response (149, 150)