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PMID: 33711021 Keywords Alpha Sympathomimetics Brimonidine Trade Names: Alphagan-P, Qoliana, Lumify & generic FDA approved in 1996 Drug Class: Alpha-2 Selective Adrenergic Agonist, Antiglaucoma, Vascular decongestant Mechanism of Action: 2 adrenoreceptor agonist approximately 10-times more selective for alpha-2 receptors compared to clonidine (Cambridge, 1981) does not exhibit significant tachyphylaxis with repeated use (Lee & Kim, 2022) Indications: Prescription & OTC to treat symptoms of: open-angle glaucoma : to lower intraocular pressure or ocular hypertension (Alphagan-P, Qoliana )

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Abstract Although diabetes mellitus is strongly associated with dementia, the mechanism underlying diabetes-induced cognitive dysfunction has not been clarified

Deficiencia [editar] Causas [editar] Existen diversos orgenes de la hipovitaminosis B 12 , ya que la falta de cualquiera de los pasos de la compleja metabolizacin que sufren las cobalaminas desde los alimentos hasta su utilizacin por las clulas, ocasiona la interrupcin de esta y por lo tanto la posibilidad de desarrollar una deficiencia de cobalaminas