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Pakistan Journal of Biochemistry & Molecular Biology

A targeted metabolomic assay performed with uniformly labeled glutamine confirmed HuRs direct link to glutamine catabolism in the TCA cycle: decreased HuR levels decreased glutamine-derived glutamate, as well as citrate and malate, in both reductive and oxidative glutamine metabolic pathways

Etanercept is FDA-approved for the treatment of rheumatoid arthritis and plaque psoriasis (Haraoui 2007

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While a protein-restricted diet reduces protein and amino acid intake to mitigate propionyl-CoA synthesis from propiogenic amino acids, fasting triggers broader metabolic alterations