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The amide bond formations in isopenicillin N (IPN) is catalyzed by three modules NRPS PcbAB

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PLoS One 8, e64344 (2013), Application(s): Fluorescence Microscopy

In previous studies, the mechanisms of immune tolerance were widely divided into innate and adaptive tolerance, while the latter can be comprehensively categorized into central and peripheral tolerance [29]

Catalyzed by DNA methyltransferases (DNMT1, DNMT2, DNMT3a, DNMT3b), it involves the transfer of a methyl group from S-adenosylmethionine (SAM) to the 5 carbon position of cytosine residues, subsequently silencing gene expression by impeding transcription factor binding