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The AMPK pathway is triggered during an energy crisis (e.g., low ATP levels, high AMP levels or nutrient deprivation), inhibiting mTOR activity and inducing catabolic processes such as autophagy

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Brain 134:12931314 Beers DR, Zhao W, Liao B et al (2011) Neuroinflammation modulates distinct regional and temporal clinical responses in ALS mice

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doi: 10.3389/fcvm.2021.821663

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