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However, the specific subcellular compartment in which the GCH1-BH4 system works remains to be determined

Recently, the FDA approved omaveloxolone, a potent activator of Nrf2 signaling, as the first therapeutic agent for FRDA (392), marking a significant step toward targeting redox imbalance and ferroptosis in this disease

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Injections offer faster absorption because they bypass the digestive system