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Ziaei S, Hasani M, Malekahmadi M, Daneshzad E, Kadkhodazadeh K, Heshmati J

Some research shows mixed results thoughone study found that quercetin blocked GLUT9 but didn't affect URAT1 levels much [11]

Induced genomic instability is manifested as the expression of the following delayed effects: delayed reproductive death or lethal mutation, chromosomal instability, and mutagenesis

however, these same proprieties can severely hinder the efficiency of the interactions with the target cells once NPs reach the desired tissues, by reducing the tissue penetration because of the higher hydrodynamic diameter, and looser associations with cell membrane because of the repulsive electrostatic charges