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Then, as demonstrated by the CCK-8 assay, the knockdown effect of FTO resulted in the enhanced proliferation capacity in KTC-1 cells, which could be reverted by SLC7A11-knockdown

doi: 10.2174/0929867324666170718104412 93 NaeimiSAHajimehdipoorHSaberS

These positive effects of AST significantly decreased in the AST + FLU (0.5 mg/kg) and AST + NAL (0.1 mg/kg) groups (Figure 10)

Harmonic restraints of 50.0 kcal mol 1 2 were applied to the solutes, including the crystallographic ions, to allow solvent relaxation while preserving the maximum fidelity to the docking pose, and the Andersen temperature coupling scheme 81,82 was used to control and equalize the temperature