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But the science matters for evaluating where this is heading, so I want to compress it into a few paragraphs

10.1167/iovs.13-12084 34 GaoA

Orthogonal validation of NMR fragment hit 27 Encouraged by the relatively high binding affinity of compound 27 compared to expectations for fragments, we synthesised a series of analogues to explore the effect of modifying both the sulfonic acid and the ethoxy substituents on binding affinity (Table 1)

The goal now is to create new pathways of thinking and action

If they do, this would also add evidence that this NNMT inhibitor improves muscle performance through increasing NAD+ levels