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doi: 10.1093/hmg/ddab054 68 BoniniMGSargisRM

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and Stillman, D., "The Saccharomyces cerevisiae SIN3 gene, a negative regulator of HO, contains four paired amphipathic helix motifs", Molecular and Cellular Biology 10: 5927-5936 (1990)

In response to pathological stress, astrocytes adopt a reactive phenotype characterized by hypertrophy of cell bodies, thickening and retraction of processes, and reorganization of glial fibrillary acidic protein (GFAP) -rich cytoskeletal networks (Sofroniew and Vinters, 2010