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Vestergaard M, Baar WFC, Holm SK, Madsen CG, Paulson OB, Born AP, et al

This is followed by adrenal insufficiency, characterized by decreased cortisol levels, suppression of the HPA axis, and reduced tissue glucocorticoid sensitivity in the subacute/chronic phase (312, 313)

The correlation between chemoresistance and increased mitochondrial activity is especially interesting in the context of TP53 mut AML as loss of p53 leads to increased glycolysis and OXPHOS in both solid tumors and a recent AML model [11,12,13]

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Although at this point in time, the ice rinks refrigeration systems are the most efficient they can be, there is still room for improvement