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Exenatide pretreatment of H9c2 cardiomyocytes diminishes H2O2-induced ROS production and upregulates the expression of antioxidant enzymes such as glutathione peroxidase-1 and manganese superoxide dismutase [164]

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Crucially, many trials may have included older adults, but had an upper age limit in their inclusion/exclusion criteria, resulting in little data for people in their 80s

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[2] [3] Types of Reaction and offending medication [edit] Immune-mediated drug hypersensitivity [edit] Commonly prescribed medications for HIV, such as sulfonamides, anticonvulsants, antibacterials, antifungals, antimycobacterials, and, most notably, antiretrovirals, have an increased incidence of adverse cutaneous drug reactions in HIV-positive individuals, and even greater escalation of incidence in people with advanced disease progression in the form of AIDS