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31 Molecular mechanisms of NADPH homeostasis in cancer Understanding NADPH production and consumption routes is essential to a global understanding of cancer metabolism

The release of neutrophil elastase and matrix metalloproteinases disrupts epithelial barrier integrity, permitting further oxidative insult (134)

About one third of AIH patients present acutely with jaundice, severe fatigue, nausea, and abdominal pain, meeting the criteria of acute severe AIH, which is defined by jaundice and INR between 1.5 and 2 in absence of known pre-existing liver disease

Considering the potential heterogeneity between multiple histological slides within each individual tumor, we set the molecular subtype label for each slide from the overall multiomics subtyping call of the corresponding tumor sample and then performed a random sampling method to identify outliers