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Additionally, a study found that in SCI animal models, the IncGm36569/miRNA-5627-5p/FSP1 axis was inhibited through molecular sponge action, thereby targeting this axis to inhibit neuronal ferroptosis (Shao et al., 2022)

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However, M2 macrophages are also implicated in promoting fibrosis, potentially via TGF- production or, a topic of ongoing discussion, direct transdifferentiation into myofibroblasts [10]