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In a clinical trial of 71 women with mild to advanced photoaging, a GHK-Cu facial cream applied daily for twelve weeks significantly increased skin density and thickness while reducing fine lines, wrinkles, and laxity

In 2024 a research group in Iran did a well designed and controlled trial comparing 5cc of placental derived exosomes with 5cc of normal saline

The synthetic versus natural distinction GHK-Cu exists naturally in human blood plasma, saliva, and urine

The absence of a label means there is no FDA-reviewed summary of indications, contraindications, dosing, drug interactions, warnings, or adverse-event data

Metzendorf NG, Godec A, Petrovic A et al (2025) Somatostatin therapy, neprilysin activation, and amyloid beta reduction: a novel approach for Alzheimers treatment