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Annu Rev Genomics Hum Genet 2001

Reduces Risk of Heart Disease and Alzheimers : Lowers the risk of heart disease and Alzheimers disease by reducing oxidative stress and protecting brain health

Besedovsky H, del Rey A, Sorkin E, Dinarello CA: Immunoregulatory feedback between interleukin-1 and glucocorticoid hormones

For example, 21monthold VEGFA hyper mice showed severe degenerative and atrophic changes of the RPE, thick basal laminar subRPE deposits, shortening of photoreceptor outer and inner segments, and attenuation of the photoreceptor outer nuclear layer (ONL) (Fig 9B and Appendix Figs S2 and S3)

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